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Unleashing a novel function of Endonuclease G in mitochondrial genome instability
Having its genome makes the mitochondrion a unique and semiautonomous organelle within cells. Mammalian mitochondrial DNA (mtDNA) is a double-stranded closed circular molecule of about 16 kb coding for 37 genes. Mutations, including deletions in the mitochondrial genome, can culminate in different h...
Autores principales: | Dahal, Sumedha, Siddiqua, Humaira, Sharma, Shivangi, Babu, Ravi K, Rathore, Diksha, Sharma, Sheetal, Raghavan, Sathees C |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9711528/ https://www.ncbi.nlm.nih.gov/pubmed/36394256 http://dx.doi.org/10.7554/eLife.69916 |
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