Synergistic activation of RARβ and RARγ nuclear receptors restores cell specialization during stem cell differentiation by hijacking RARα-controlled programs

How cells respond to different external cues to develop along defined cell lineages to form complex tissues is a major question in systems biology. Here, we investigated the potential of retinoic acid receptor (RAR)–selective synthetic agonists to activate the gene regulatory programs driving cell s...

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Detalles Bibliográficos
Autores principales: Koshy, Aysis, Mathieux, Elodie, Stüder, François, Bramoulle, Aude, Lieb, Michele, Colombo, Bruno Maria, Gronemeyer, Hinrich, Mendoza-Parra, Marco Antonio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Life Science Alliance LLC 2022
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9711859/
https://www.ncbi.nlm.nih.gov/pubmed/36446525
http://dx.doi.org/10.26508/lsa.202201627

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9711859/
https://www.ncbi.nlm.nih.gov/pubmed/36446525
http://dx.doi.org/10.26508/lsa.202201627

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