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Loss of cell–cell adhesion triggers cell migration through Rac1-dependent ROS generation

Epithelial cells usually trigger their “migratory machinery” upon loss of adhesion to their neighbors. This default is important for both physiological (e.g., wound healing) and pathological (e.g., tumor metastasis) processes. However, the underlying mechanism for such a default remains unclear. In...

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Detalles Bibliográficos
Autores principales: Chen, Yu-Hsuan, Hsu, Jinn-Yuan, Chu, Ching-Tung, Chang, Yao-Wen, Fan, Jia-Rong, Yang, Muh-Hwa, Chen, Hong-Chen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Life Science Alliance LLC 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9711860/
https://www.ncbi.nlm.nih.gov/pubmed/36446524
http://dx.doi.org/10.26508/lsa.202201529