Protective α1-antitrypsin effects in autoimmune vasculitis are compromised by methionine oxidation

BACKGROUND: Antineutrophil cytoplasmic autoantibody–associated (ANCA-associated) vasculitidies (AAV) are life-threatening systemic autoimmune conditions. ANCAs directed against proteinase 3 (PR3) or myeloperoxidase (MPO) bind their cell surface-presented antigen, activate neutrophils, and cause vasc...

Descripción completa

Detalles Bibliográficos
Autores principales: Ebert, Maximilian, Jerke, Uwe, Eulenberg-Gustavus, Claudia, Kling, Lovis, Jenne, Dieter, Kirchner, Marieluise, Mertins, Philipp, Bieringer, Markus, Elitok, Saban, Eckardt, Kai-Uwe, Schreiber, Adrian, Salama, Alan D., Kettritz, Ralph
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2022
Materias:
Clinical Medicine
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9711875/
https://www.ncbi.nlm.nih.gov/pubmed/36125911
http://dx.doi.org/10.1172/JCI160089

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9711875/
https://www.ncbi.nlm.nih.gov/pubmed/36125911
http://dx.doi.org/10.1172/JCI160089

Ejemplares similares