A mitofusin 2/HIF1α axis sets a maturation checkpoint in regenerating skeletal muscle

A fundamental issue in regenerative medicine is whether there exist endogenous regulatory mechanisms that limit the speed and efficiency of the repair process. We report the existence of a maturation checkpoint during muscle regeneration that pauses myofibers at a neonatal stage. This checkpoint is...

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Detalles Bibliográficos
Autores principales: Wang, Xun, Jia, Yuemeng, Zhao, Jiawei, Lesner, Nicholas P., Menezes, Cameron J., Shelton, Spencer D., Venigalla, Siva Sai Krishna, Xu, Jian, Cai, Chunyu, Mishra, Prashant
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9711883/
https://www.ncbi.nlm.nih.gov/pubmed/36125902
http://dx.doi.org/10.1172/JCI161638

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9711883/
https://www.ncbi.nlm.nih.gov/pubmed/36125902
http://dx.doi.org/10.1172/JCI161638

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