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A mitofusin 2/HIF1α axis sets a maturation checkpoint in regenerating skeletal muscle

A fundamental issue in regenerative medicine is whether there exist endogenous regulatory mechanisms that limit the speed and efficiency of the repair process. We report the existence of a maturation checkpoint during muscle regeneration that pauses myofibers at a neonatal stage. This checkpoint is...

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Detalles Bibliográficos
Autores principales:	Wang, Xun, Jia, Yuemeng, Zhao, Jiawei, Lesner, Nicholas P., Menezes, Cameron J., Shelton, Spencer D., Venigalla, Siva Sai Krishna, Xu, Jian, Cai, Chunyu, Mishra, Prashant
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Clinical Investigation 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9711883/ https://www.ncbi.nlm.nih.gov/pubmed/36125902 http://dx.doi.org/10.1172/JCI161638

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