Peptide from NSP7 is able to form amyloid-like fibrils: Artifact or challenge to drug design?

• We found potential amyloidogenic fragment in NSP7 SARS-CoV2 protein in silico; • NSP7 (52–62) fragment is able to form amyloid-like fibrils; • The possibility of using such a peptide as the basis for an antiviral drug is discussed.

Detalles Bibliográficos
Autores principales: Garmay, Yuri, Rubel, Aleksandr, Egorov, Vladimir
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier B.V. 2023
Materias:
BBA Research Letter
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9711895/
https://www.ncbi.nlm.nih.gov/pubmed/36462605
http://dx.doi.org/10.1016/j.bbapap.2022.140884

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9711895/
https://www.ncbi.nlm.nih.gov/pubmed/36462605
http://dx.doi.org/10.1016/j.bbapap.2022.140884

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