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Peptide from NSP7 is able to form amyloid-like fibrils: Artifact or challenge to drug design?
• We found potential amyloidogenic fragment in NSP7 SARS-CoV2 protein in silico; • NSP7 (52–62) fragment is able to form amyloid-like fibrils; • The possibility of using such a peptide as the basis for an antiviral drug is discussed.
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier B.V.
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9711895/ https://www.ncbi.nlm.nih.gov/pubmed/36462605 http://dx.doi.org/10.1016/j.bbapap.2022.140884 |