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Intra-articular injection of clioquinol ameliorates osteoarthritis in a rabbit model

Osteoarthritis (OA) is characterized by the degeneration of articular cartilage. Decreased autophagy is tightly associated with chondrocyte death, which contributes to the progression of OA. Thus, pharmacological activation of autophagy may be a promising therapeutic approach for OA. Here, we discov...

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Detalles Bibliográficos
Autores principales: Wu, Xiaoqing, Xu, Peng, Shi, Xuanren, Shang, Jian, Chen, Xiaoyong, Guo, Anyun, Wang, Fuming, Yin, Zhanhai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9712181/
https://www.ncbi.nlm.nih.gov/pubmed/36465935
http://dx.doi.org/10.3389/fmed.2022.1028575