Polyploidy, regular patterning of genome copies, and unusual control of DNA partitioning in the Lyme disease spirochete

Borrelia burgdorferi, the tick-transmitted spirochete agent of Lyme disease, has a highly segmented genome with a linear chromosome and various linear or circular plasmids. Here, by imaging several chromosomal loci and 16 distinct plasmids, we show that B. burgdorferi is polyploid during growth in c...

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Detalles Bibliográficos
Autores principales: Takacs, Constantin N., Wachter, Jenny, Xiang, Yingjie, Ren, Zhongqing, Karaboja, Xheni, Scott, Molly, Stoner, Matthew R., Irnov, Irnov, Jannetty, Nicholas, Rosa, Patricia A., Wang, Xindan, Jacobs-Wagner, Christine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9712426/
https://www.ncbi.nlm.nih.gov/pubmed/36450725
http://dx.doi.org/10.1038/s41467-022-34876-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9712426/
https://www.ncbi.nlm.nih.gov/pubmed/36450725
http://dx.doi.org/10.1038/s41467-022-34876-4

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