Regulatory T cells in psoriatic arthritis: an IL-17A-producing, Foxp3(int)CD161 + RORγt + ICOS + phenotype, that associates with the presence of ADAMTSL5 autoantibodies

In psoriatic arthritis (PsA), predisposing class I HLA alleles, the presence of synovial clonally proliferated CD8 + T cells and autoantibodies all point towards the loss of immune tolerance. However, the key mechanisms that lead to immune dysregulation are not fully understood. In other types of in...

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Detalles Bibliográficos
Autores principales: Pouw, Juliëtte N., Olde Nordkamp, Michel A. M., van Kempen, Tessa, Concepcion, Arno N., van Laar, Jacob M., van Wijk, Femke, Spierings, Julia, Leijten, Emmerik F. A., Boes, Marianne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9712434/
https://www.ncbi.nlm.nih.gov/pubmed/36450783
http://dx.doi.org/10.1038/s41598-022-24924-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9712434/
https://www.ncbi.nlm.nih.gov/pubmed/36450783
http://dx.doi.org/10.1038/s41598-022-24924-w

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