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Therapeutic drug monitoring of perampanel in children diagnosed with epilepsy: Focus on influencing factors on the plasma concentration‐to‐dose ratio

OBJECTIVE: This study aimed to investigate the efficacy and tolerability of perampanel (PER) therapy and to optimize a specific plasma reference range for PER in children. Another major aim was to evaluate the potential determinators of PER concentration. METHODS: Concentrations obtained from 80 chi...

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Detalles Bibliográficos
Autores principales: Li, Yue, Dong, Na, Qin, Yu‐Xin, Dai, Hao‐Ran, Hu, Ya‐Hui, Zhao, Yue‐Tao, Guo, Hong‐Li, Zhang, Yuan‐Yuan, Chen, Jing, Lu, Xiao‐Peng, Chen, Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9712465/
https://www.ncbi.nlm.nih.gov/pubmed/36177517
http://dx.doi.org/10.1002/epi4.12653