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Efficacy and tolerability of brivaracetam monotherapy in childhood and juvenile absence epilepsy: An innovative adaptive trial design

OBJECTIVE: Despite introduction of several antiseizure medications over the past two decades, treatment options for childhood absence epilepsy (CAE) and juvenile absence epilepsy (JAE) remain limited. We report the innovative adaptive design of an ongoing phase 2/3 trial to evaluate efficacy, safety...

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Detalles Bibliográficos
Autores principales: Bast, Thomas, Schulz, Anne‐Liv, Floricel, Florin, Morita, Diego, Cleveland, Jody M., Elshoff, Jan‐Peer
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9712476/
https://www.ncbi.nlm.nih.gov/pubmed/35844134
http://dx.doi.org/10.1002/epi4.12628