Non-human primate to human immunobridging demonstrates a protective effect of Ad26.ZEBOV, MVA-BN-Filo vaccine against Ebola

Without clinical efficacy data, vaccine protective effect may be extrapolated from animals to humans using an immunologic marker that correlates with protection in animals. This immunobridging approach was used for the two-dose Ebola vaccine regimen Ad26.ZEBOV, MVA-BN-Filo. Ebola virus (EBOV) glycop...

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Detalles Bibliográficos
Autores principales: Bockstal, Viki, Leyssen, Maarten, Heerwegh, Dirk, Spiessens, Bart, Robinson, Cynthia, Stoop, Jeroen N., Roozendaal, Ramon, Van Effelterre, Thierry, Gaddah, Auguste, Van Roey, Griet A., Solforosi, Laura, Zahn, Roland, Callendret, Benoit, Hendriks, Jenny, Luhn, Kerstin, Douoguih, Macaya, Schuitemaker, Hanneke, Van Hoof, Johan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9712521/
https://www.ncbi.nlm.nih.gov/pubmed/36450746
http://dx.doi.org/10.1038/s41541-022-00564-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9712521/
https://www.ncbi.nlm.nih.gov/pubmed/36450746
http://dx.doi.org/10.1038/s41541-022-00564-z

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