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Deciphering the heterogeneity of the Lyve1(+) perivascular macrophages in the mouse brain

Perivascular macrophages (pvMs) are associated with cerebral vasculature and mediate brain drainage and immune regulation. Here, using reporter mouse models, whole brain and section immunofluorescence, flow cytometry, and single cell RNA sequencing, besides the Lyve1(+)F4/80(+)CD206(+)CX3CR1(+) pvMs...

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Detalles Bibliográficos
Autores principales: Siret, C., van Lessen, M., Bavais, J., Jeong, H. W., Reddy Samawar, S. K., Kapupara, K., Wang, S., Simic, M., de Fabritus, L., Tchoghandjian, A., Fallet, M., Huang, H., Sarrazin, S., Sieweke, M. H., Stumm, R., Sorokin, L., Adams, R. H., Schulte-Merker, S., Kiefer, F., van de Pavert, S. A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9712536/
https://www.ncbi.nlm.nih.gov/pubmed/36450771
http://dx.doi.org/10.1038/s41467-022-35166-9