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Genetic analysis of the PCSK9 locus in psychological, psychiatric, metabolic and cardiovascular traits in UK Biobank

The association between severe mental illness (SMI) and cardiovascular and metabolic disease (CMD) is poorly understood. PCSK9 is expressed in systems critical to both SMI and CMD and influences lipid homeostasis and brain function. We systematically investigated relationships between genetic variat...

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Detalles Bibliográficos
Autores principales: Hay, Rachel, Cullen, Breda, Graham, Nicholas, Lyall, Donald M., Aman, Alisha, Pell, Jill P., Ward, Joey, Smith, Daniel J., Strawbridge, Rona J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9712543/
https://www.ncbi.nlm.nih.gov/pubmed/35501368
http://dx.doi.org/10.1038/s41431-022-01107-9