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Genetic analysis of the PCSK9 locus in psychological, psychiatric, metabolic and cardiovascular traits in UK Biobank
The association between severe mental illness (SMI) and cardiovascular and metabolic disease (CMD) is poorly understood. PCSK9 is expressed in systems critical to both SMI and CMD and influences lipid homeostasis and brain function. We systematically investigated relationships between genetic variat...
Autores principales: | Hay, Rachel, Cullen, Breda, Graham, Nicholas, Lyall, Donald M., Aman, Alisha, Pell, Jill P., Ward, Joey, Smith, Daniel J., Strawbridge, Rona J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer International Publishing
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9712543/ https://www.ncbi.nlm.nih.gov/pubmed/35501368 http://dx.doi.org/10.1038/s41431-022-01107-9 |
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