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Intermittent scavenging of storage lesion from stored red blood cells by electrospun nanofibrous sheets enhances their quality and shelf-life

Transfusion of healthy red blood cells (RBCs) is a lifesaving process. However, upon storing RBCs, a wide range of damage-associate molecular patterns (DAMPs), such as cell-free DNA, nucleosomes, free-hemoglobin, and poly-unsaturated-fatty-acids are generated. DAMPs can further damage RBCs; thus, th...

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Detalles Bibliográficos
Autores principales: Pandey, Subhashini, Mahato, Manohar, Srinath, Preethem, Bhutani, Utkarsh, Goap, Tanu Jain, Ravipati, Priusha, Vemula, Praveen Kumar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9712616/
https://www.ncbi.nlm.nih.gov/pubmed/36450757
http://dx.doi.org/10.1038/s41467-022-35269-3