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Butein promotes ubiquitination-mediated survivin degradation inhibits tumor growth and overcomes chemoresistance
Overexpression of survivin is frequently observed in human malignancies and is associated with poor prognosis. The present study found that survivin is highly expressed in nasopharyngeal carcinoma (NPC) tumor tissues. Depleting survivin with shRNA inhibited cell viability, colony formation, and in v...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9712619/ https://www.ncbi.nlm.nih.gov/pubmed/36450751 http://dx.doi.org/10.1038/s41598-022-21839-4 |