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Physiological intron retaining transcripts in the cytoplasm abound during human motor neurogenesis

Intron retention (IR) is now recognized as a dominant splicing event during motor neuron (MN) development; however, the role and regulation of intron-retaining transcripts (IRTs) localized to the cytoplasm remain particularly understudied. Here we show that IR is a physiological process that is spat...

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Detalles Bibliográficos
Autores principales: Petrić Howe, Marija, Crerar, Hamish, Neeves, Jacob, Harley, Jasmine, Tyzack, Giulia E., Klein, Pierre, Ramos, Andres, Patani, Rickie, Luisier, Raphaëlle
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9712626/
https://www.ncbi.nlm.nih.gov/pubmed/36180233
http://dx.doi.org/10.1101/gr.276898.122