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Cheminformatics analysis of chemicals that increase estrogen and progesterone synthesis for a breast cancer hazard assessment

Factors that increase estrogen or progesterone (P4) action are well-established as increasing breast cancer risk, and many first-line treatments to prevent breast cancer recurrence work by blocking estrogen synthesis or action. In previous work, using data from an in vitro steroidogenesis assay deve...

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Detalles Bibliográficos
Autores principales: Borrel, Alexandre, Rudel, Ruthann A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9712655/
https://www.ncbi.nlm.nih.gov/pubmed/36450809
http://dx.doi.org/10.1038/s41598-022-24889-w