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The E3 ubiquitin ligase WWP2 regulates pro-fibrogenic monocyte infiltration and activity in heart fibrosis

Non-ischemic cardiomyopathy (NICM) can cause left ventricular dysfunction through interstitial fibrosis, which corresponds to the failure of cardiac tissue remodeling. Recent evidence implicates monocytes/macrophages in the etiopathology of cardiac fibrosis, but giving their heterogeneity and the an...

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Detalles Bibliográficos
Autores principales: Chen, Huimei, Chew, Gabriel, Devapragash, Nithya, Loh, Jui Zhi, Huang, Kevin Y., Guo, Jing, Liu, Shiyang, Tan, Elisabeth Li Sa, Chen, Shuang, Tee, Nicole Gui Zhen, Mia, Masum M., Singh, Manvendra K., Zhang, Aihua, Behmoaras, Jacques, Petretto, Enrico
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9712659/
https://www.ncbi.nlm.nih.gov/pubmed/36450710
http://dx.doi.org/10.1038/s41467-022-34971-6