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Low-dose aspirin protects unexplained recurrent spontaneous abortion via downregulation of HMGB1 inflammation activation

BACKGROUND: High mobility group box protein 1 (HMGB1) is considered as a kind of sterile inflammatory mediators, which is an overexpression in patients with unexplained recurrent spontaneous abortion (URSA). Specific targeting effect of aspirin on HMGB1 has been revealed. Our previous studies have e...

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Detalles Bibliográficos
Autores principales: Xu, Xiaofeng, Wang, Jing, Zhu, Damin, Yin, Jiaqian, Liu, Jinxian, Wu, Xiao, Yang, Wenjuan, Hu, Qian, Ren, Yu, Zhang, Zhiguo, Zhou, Ping, Wei, Zhaolian, Zou, Huijuan, Cao, Yunxia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9712724/
https://www.ncbi.nlm.nih.gov/pubmed/36465622
http://dx.doi.org/10.3389/fendo.2022.914030