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Sex differences in a double-blind randomized clinical trial with minocycline in treatment-resistant depressed patients: CRP and IL-6 as sex-specific predictors of treatment response

BACKGROUND: Inflammation is a well-known risk factor for depression. Specifically, patients who do not respond to antidepressant treatment show higher levels of inflammatory biomarkers compared with responders. Thus, several studies have investigated the efficacy of anti-inflammatory add-on treatmen...

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Detalles Bibliográficos
Autores principales: Lombardo, Giulia, Nettis, Maria Antonietta, Hastings, Caitlin, Zajkowska, Zuzanna, Mariani, Nicole, Nikkheslat, Naghmeh, Worrell, Courtney, Enache, Daniela, McLaughlin, Anna, Kose, Melisa, Bogdanova, Anna, Sforzini, Luca, Cleare, Anthony J., Young, Allan H., Dazzan, Paola, Mondelli, Valeria, Pariante, Carmine M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9712814/
https://www.ncbi.nlm.nih.gov/pubmed/36467125
http://dx.doi.org/10.1016/j.bbih.2022.100561