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Extracellular adenosine induces hypersecretion of IL-17A by T-helper 17 cells through the adenosine A2a receptor

Extracellular adenosine, produced from ATP secreted by neuronal or immune cells, may play a role in endogenous regulation of inflammatory responses. Studies show that adenosine induces hypersecretion of IL-17A by CD4(+) T cells upon treatment with an A2aR agonist (PSB0777), and that adenosine-mediat...

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Detalles Bibliográficos
Autores principales: Tokano, Mieko, Matsushita, Sho, Takagi, Rie, Yamamoto, Toshimasa, Kawano, Masaaki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9712818/
https://www.ncbi.nlm.nih.gov/pubmed/36467126
http://dx.doi.org/10.1016/j.bbih.2022.100544