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Extracellular adenosine induces hypersecretion of IL-17A by T-helper 17 cells through the adenosine A2a receptor
Extracellular adenosine, produced from ATP secreted by neuronal or immune cells, may play a role in endogenous regulation of inflammatory responses. Studies show that adenosine induces hypersecretion of IL-17A by CD4(+) T cells upon treatment with an A2aR agonist (PSB0777), and that adenosine-mediat...
Autores principales: | Tokano, Mieko, Matsushita, Sho, Takagi, Rie, Yamamoto, Toshimasa, Kawano, Masaaki |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9712818/ https://www.ncbi.nlm.nih.gov/pubmed/36467126 http://dx.doi.org/10.1016/j.bbih.2022.100544 |
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