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Effect of Tolvaptan in Patients with Chronic Kidney Disease Stage G5, and Impact of Concomitant Use of Thiazide Diuretics: A Retrospective Cohort Study

BACKGROUND: The diuretic effect of tolvaptan, a vasopressin V2 receptor antagonist, in patients with severe renal dysfunction remains poorly characterized. Thiazide diuretics reduce urinary volume (UV) in patients with nephrogenic diabetes insipidus, which lacks V2 receptor function. OBJECTIVE: This...

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Detalles Bibliográficos
Autores principales: Uchiyama, Kiyotaka, Kojima, Daiki, Hama, Eriko Yoshida, Nagasaka, Tomoki, Nakayama, Takashin, Takahashi, Rina, Tajima, Takaya, Morimoto, Kohkichi, Washida, Naoki, Itoh, Hiroshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9712855/
https://www.ncbi.nlm.nih.gov/pubmed/35962921
http://dx.doi.org/10.1007/s40801-022-00325-3