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Incubation Temperature and Period During Denarase Treatment and Microfiltration Affect the Yield of Recombinant Adenoviral Vectors During Downstream Processing

Adenoviral vectors (AV) are commonly used as vaccine and gene therapy vehicles because of their ease of construction, ability to grow to high titers in the large-scale production process, and safety for human applications. However, the efficiency rate of downstream processes for adenoviral vectors s...

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Detalles Bibliográficos
Autores principales: Sonugür, Fatma Gizem, Babahan, Cansu, Abdi Abgarmi, Samira, Akbulut, Hakan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9713150/
https://www.ncbi.nlm.nih.gov/pubmed/36451062
http://dx.doi.org/10.1007/s12033-022-00616-8