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Transcriptomic profiling implicates PAF1 in both active and repressive immune regulatory networks

BACKGROUND: Sitting at the interface of gene expression and host-pathogen interaction, polymerase associated factor 1 complex (PAF1C) is a rising player in the innate immune response. The complex localizes to the nucleus and associates with chromatin to modulate RNA polymerase II (RNAPII) elongation...

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Detalles Bibliográficos
Autores principales: Kenaston, Matthew W., Pham, Oanh H., Petit, Marine J., Shah, Priya S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9713194/
https://www.ncbi.nlm.nih.gov/pubmed/36451099
http://dx.doi.org/10.1186/s12864-022-09013-6