DSCR1 deficiency ameliorates the Aβ pathology of Alzheimer’s disease by enhancing microglial activity

Microglial phagocytosis and clearance are important for the removal of amyloid-β (Aβ) plaques in Alzheimer’s disease (AD). Chronic exposure of microglia to Aβ plaques leads to microglial metabolic dysfunction, and dysregulation of microglia can accelerate the deposition of Aβ plaques and cause learn...

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Detalles Bibliográficos
Autores principales: Choi, Chiyeol, Kim, Hyerin, Oh, Jiyoung, Park, Chanho, Kim, Min, Kim, Chu-Sook, Park, Jiyoung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Life Science Alliance LLC 2022
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9713304/
https://www.ncbi.nlm.nih.gov/pubmed/36450444
http://dx.doi.org/10.26508/lsa.202201556

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9713304/
https://www.ncbi.nlm.nih.gov/pubmed/36450444
http://dx.doi.org/10.26508/lsa.202201556

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