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DSCR1 deficiency ameliorates the Aβ pathology of Alzheimer’s disease by enhancing microglial activity
Microglial phagocytosis and clearance are important for the removal of amyloid-β (Aβ) plaques in Alzheimer’s disease (AD). Chronic exposure of microglia to Aβ plaques leads to microglial metabolic dysfunction, and dysregulation of microglia can accelerate the deposition of Aβ plaques and cause learn...
Autores principales: | Choi, Chiyeol, Kim, Hyerin, Oh, Jiyoung, Park, Chanho, Kim, Min, Kim, Chu-Sook, Park, Jiyoung |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Life Science Alliance LLC
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9713304/ https://www.ncbi.nlm.nih.gov/pubmed/36450444 http://dx.doi.org/10.26508/lsa.202201556 |
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