Cargando…
Fluorescent pulse-chase labeling to monitor long-term mitochondrial degradation in primary hippocampal neurons
The accumulation of dysfunctional mitochondria is a hallmark of neurodegenerative diseases, yet the dynamics of mitochondrial turnover in neurons are unclear. Here, we describe a protocol to monitor the degradation of spectrally distinct, “aged” mitochondrial populations. We describe the preparation...
| Autores principales: | , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2022
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9713342/ https://www.ncbi.nlm.nih.gov/pubmed/36595944 http://dx.doi.org/10.1016/j.xpro.2022.101822 |