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Gut-specific cardenolide-resistant sodium pump primed an omnivore to feed on toxic oleander
Apocynaceae plants produce toxic cardenolides to defend against their herbivores. Cardenolides could inhibit the α subunit of Na(+)⁄K(+)-ATPase (ATPα), which plays critical roles in biological processes such as muscle contraction, neural function, and osmoregulation. Numerous herbivores that special...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9713366/ https://www.ncbi.nlm.nih.gov/pubmed/36465126 http://dx.doi.org/10.1016/j.isci.2022.105616 |