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Gut-specific cardenolide-resistant sodium pump primed an omnivore to feed on toxic oleander

Apocynaceae plants produce toxic cardenolides to defend against their herbivores. Cardenolides could inhibit the α subunit of Na(+)⁄K(+)-ATPase (ATPα), which plays critical roles in biological processes such as muscle contraction, neural function, and osmoregulation. Numerous herbivores that special...

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Detalles Bibliográficos
Autores principales: Wang, Tianyu, Shi, Lina, Zhen, Ying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9713366/
https://www.ncbi.nlm.nih.gov/pubmed/36465126
http://dx.doi.org/10.1016/j.isci.2022.105616