The signaling pathways and therapeutic potential of itaconate to alleviate inflammation and oxidative stress in inflammatory diseases

Endogenous small molecules are metabolic regulators of cell function. Itaconate is a key molecule that accumulates in cells when the Krebs cycle is disrupted. Itaconate is derived from cis-aconitate decarboxylation by cis-aconitate decarboxylase (ACOD1) in the mitochondrial matrix and is also known...

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Detalles Bibliográficos
Autores principales: Shi, Xuan, Zhou, Huanping, Wei, Juan, Mo, Wei, Li, Quanfu, Lv, Xin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9713374/
https://www.ncbi.nlm.nih.gov/pubmed/36459716
http://dx.doi.org/10.1016/j.redox.2022.102553

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9713374/
https://www.ncbi.nlm.nih.gov/pubmed/36459716
http://dx.doi.org/10.1016/j.redox.2022.102553

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