Role of pericytes in the development of cerebral cavernous malformations

Cerebral cavernous malformation (CCM) is caused by loss-of-function mutations in CCM1, CCM2, or CCM3 genes of endothelial cells. It is characterized by pericyte deficiency. However, the role of pericytes in CCMs is not yet clarified. We found pericytes in Cdh5Cre(ERT2);Ccm1(fl/fl) (Ccm1(ECKO)) mice...

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Detalles Bibliográficos
Autores principales: Dai, Zifeng, Li, Jingwei, Li, Ying, Wang, Rui, Yan, Huili, Xiong, Ziyu, Wu, Shiting, Yang, Xi, Lu, Dongbo, Zhang, Dongdong, Li, Guofu, Wang, Yuwen, Men, Chunyang, Du, Wenzhong, Zheng, Xiangjian, Shi, Changbin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9713377/
https://www.ncbi.nlm.nih.gov/pubmed/36465134
http://dx.doi.org/10.1016/j.isci.2022.105642

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9713377/
https://www.ncbi.nlm.nih.gov/pubmed/36465134
http://dx.doi.org/10.1016/j.isci.2022.105642

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