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Role of pericytes in the development of cerebral cavernous malformations
Cerebral cavernous malformation (CCM) is caused by loss-of-function mutations in CCM1, CCM2, or CCM3 genes of endothelial cells. It is characterized by pericyte deficiency. However, the role of pericytes in CCMs is not yet clarified. We found pericytes in Cdh5Cre(ERT2);Ccm1(fl/fl) (Ccm1(ECKO)) mice...
Autores principales: | Dai, Zifeng, Li, Jingwei, Li, Ying, Wang, Rui, Yan, Huili, Xiong, Ziyu, Wu, Shiting, Yang, Xi, Lu, Dongbo, Zhang, Dongdong, Li, Guofu, Wang, Yuwen, Men, Chunyang, Du, Wenzhong, Zheng, Xiangjian, Shi, Changbin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9713377/ https://www.ncbi.nlm.nih.gov/pubmed/36465134 http://dx.doi.org/10.1016/j.isci.2022.105642 |
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