Genetic determinants of polygenic prediction accuracy within a population

Genomic risk prediction is on the emerging path toward personalized medicine. However, the accuracy of polygenic prediction varies strongly in different individuals. Based on up to 352,277 European ancestry participants in the UK Biobank, we constructed polygenic risk scores for 15 physiological and...

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Detalles Bibliográficos
Autores principales: Lu, Tianyuan, Forgetta, Vincenzo, Richards, John Brent, Greenwood, Celia M T
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Investigation
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9713421/
https://www.ncbi.nlm.nih.gov/pubmed/36250789
http://dx.doi.org/10.1093/genetics/iyac158

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9713421/
https://www.ncbi.nlm.nih.gov/pubmed/36250789
http://dx.doi.org/10.1093/genetics/iyac158

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