Transcriptional Behavior of Regulatory T Cells Predicts IBD Patient Responses to Vedolizumab Therapy

BACKGROUND: Inflammatory bowel disease (IBD) involves chronic T cell–mediated inflammatory responses. Vedolizumab (VDZ), a monoclonal antibody against α4β7 integrin, inhibits lymphocyte extravasation into intestinal mucosae and is effective in ulcerative colitis (UC) and Crohn’s disease (CD). AIM: W...

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Detalles Bibliográficos
Autores principales: Abreu, Maria T, Davies, Julie M, Quintero, Maria A, Delmas, Amber, Diaz, Sophia, Martinez, Catherine D, Venables, Thomas, Reich, Adrian, Crynen, Gogce, Deshpande, Amar R, Kerman, David H, Damas, Oriana M, Fernandez, Irina, Santander, Ana M, Pignac-Kobinger, Judith, Burgueno, Juan F, Sundrud, Mark S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Leading Off
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9713523/
https://www.ncbi.nlm.nih.gov/pubmed/35993552
http://dx.doi.org/10.1093/ibd/izac151

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9713523/
https://www.ncbi.nlm.nih.gov/pubmed/35993552
http://dx.doi.org/10.1093/ibd/izac151

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