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Thymosin β4 is essential for thrombus formation by controlling the G-actin/F-actin equilibrium in platelets

Coordinated rearrangements of the actin cytoskeleton are pivotal for platelet biogenesis from megakaryocytes but also orchestrate key functions of peripheral platelets in hemostasis and thrombosis, such as granule release, the formation of filopodia and lamellipodia, or clot retraction. Along with p...

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Detalles Bibliográficos
Autores principales: Scheller, Inga, Beck, Sarah, Göb, Vanessa, Gross, Carina, Neagoe, Raluca A. I., Aurbach, Katja, Bender, Markus, Stegner, David, Nagy, Zoltan, Nieswandt, Bernhard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Fondazione Ferrata Storti 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9713564/
https://www.ncbi.nlm.nih.gov/pubmed/34348450
http://dx.doi.org/10.3324/haematol.2021.278537