The E3 ubiquitin ligase RNF115 regulates phagosome maturation and host response to bacterial infection

Phagocytosis is a key process in innate immunity and homeostasis. After particle uptake, newly formed phagosomes mature by acquisition of endolysosomal enzymes. Macrophage activation by interferon gamma (IFN‐γ) increases microbicidal activity, but delays phagosomal maturation by an unknown mechanism...

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Detalles Bibliográficos
Autores principales: Bilkei‐Gorzo, Orsolya, Heunis, Tiaan, Marín‐Rubio, José Luis, Cianfanelli, Francesca Romana, Raymond, Benjamin Bernard Armando, Inns, Joseph, Fabrikova, Daniela, Peltier, Julien, Oakley, Fiona, Schmid, Ralf, Härtlova, Anetta, Trost, Matthias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9713710/
https://www.ncbi.nlm.nih.gov/pubmed/36281581
http://dx.doi.org/10.15252/embj.2021108970

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9713710/
https://www.ncbi.nlm.nih.gov/pubmed/36281581
http://dx.doi.org/10.15252/embj.2021108970

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