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Phospholipid imbalance impairs autophagosome completion

Autophagy, a conserved eukaryotic intracellular catabolic pathway, maintains cell homeostasis by lysosomal degradation of cytosolic material engulfed in double membrane vesicles termed autophagosomes, which form upon sealing of single‐membrane cisternae called phagophores. While the role of phosphat...

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Detalles Bibliográficos
Autores principales: Polyansky, Alexandra, Shatz, Oren, Fraiberg, Milana, Shimoni, Eyal, Dadosh, Tali, Mari, Muriel, Reggiori, Fulvio M, Qin, Chao, Han, Xianlin, Elazar, Zvulun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9713711/
https://www.ncbi.nlm.nih.gov/pubmed/36300838
http://dx.doi.org/10.15252/embj.2022110771