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Hypoxia promotes osteogenesis by facilitating acetyl‐CoA‐mediated mitochondrial–nuclear communication

Bone‐derived mesenchymal stem cells (MSCs) reside in a hypoxic niche that maintains their differentiation potential. While hypoxia (low oxygen concentration) was reported to critically support stem cell function and osteogenesis, the molecular events triggering changes in stem cell fate decisions in...

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Detalles Bibliográficos
Autores principales: Pouikli, Andromachi, Maleszewska, Monika, Parekh, Swati, Yang, Ming, Nikopoulou, Chrysa, Bonfiglio, Juan Jose, Mylonas, Constantine, Sandoval, Tonantzi, Schumacher, Anna‐Lena, Hinze, Yvonne, Matic, Ivan, Frezza, Christian, Tessarz, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9713713/
https://www.ncbi.nlm.nih.gov/pubmed/36278281
http://dx.doi.org/10.15252/embj.2022111239