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One-pot chemical pyro- and tri-phosphorylation of peptides by using diamidophosphate in water

Protein (pyro)phosphorylation is emerging as a post-translational modification (PTM) in signalling pathways involved in many cellular processes. However, access to synthetic pyrophosphopeptides that can serve as tools for understanding protein pyrophosphorylation is quite limited. Herein, we report...

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Detalles Bibliográficos
Autores principales: Lin, Huacan, Leman, Luke J., Krishnamurthy, Ramanarayanan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9713773/
https://www.ncbi.nlm.nih.gov/pubmed/36544739
http://dx.doi.org/10.1039/d2sc04160j