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Functions and modulation of PKM2 activity by human papillomavirus E7 oncoprotein (Review)

Most tumor cells still exhibit active glucose uptake and glycolysis under aerobic conditions, a phenomenon known as the Warburg effect or aerobic glycolysis. Pyruvate kinase, one of the key enzymes in the cell glycolysis pathway, can promote the conversion of glucose to pyruvate and produce energy....

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Detalles Bibliográficos
Autores principales: Gui, Chengzhi, Ji, Mingyu, Song, Yiying, Wang, Jing, Zhou, Yunying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9713779/
https://www.ncbi.nlm.nih.gov/pubmed/36478899
http://dx.doi.org/10.3892/ol.2022.13593