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Effects of BRAF V600E and NRAS mutational status on the progression-free survival and clinicopathological characteristics of patients with melanoma

Hotspot mutations of the BRAF and NRAS genes are the most common genetic alterations in invasive cutaneous melanoma; however, the prognostic significance of BRAF and NRAS co-mutations remains controversial. The present study aimed to determine the association between NRAS and BRAF mutation status an...

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Detalles Bibliográficos
Autores principales: Zablocka, Tatjana, Kreismane, Madara, Pjanova, Dace, Isajevs, Sergejs
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9713804/
https://www.ncbi.nlm.nih.gov/pubmed/36478905
http://dx.doi.org/10.3892/ol.2022.13613