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Suppressing circ_0008494 inhibits HSCs activation by regulating the miR-185-3p/Col1a1 axis

Background: Hepatic fibrosis (HF) is characterized by activation of hepatic stellate cells (HSCs) and extensive deposition of extracellular matrix components, especially collagens. However, effective antifibrotic therapies are still lacking. Recently, circular RNAs (circRNAs) have been identified as...

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Detalles Bibliográficos
Autores principales: Li, Binbin, Zhou, Jiaming, Luo, Yuanyuan, Tao, Kegong, Zhang, Lifen, Zhao, Ying, Lin, Yong, Zeng, Xin, Yu, Hongyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9713816/
https://www.ncbi.nlm.nih.gov/pubmed/36467040
http://dx.doi.org/10.3389/fphar.2022.1050093