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T cell-intrinsic protein kinase D3 is dispensable for the cells’ activation

Protein kinases D (PKDs) are implicated in T cell receptor (TCR) signaling. Of the two T cell-expressed isoforms PKD2 and PKD3, however, only the former one is rather well understood in this immune cell type. Recently, we have observed a putative hyper-phenotype of T cells from conventional PKD3-kno...

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Detalles Bibliográficos
Autores principales: Koutník, Jiří, Leitges, Michael, Siegmund, Kerstin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9713823/
https://www.ncbi.nlm.nih.gov/pubmed/36466811
http://dx.doi.org/10.3389/fimmu.2022.1049033