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Xanthohumol improves cognition in farnesoid X receptor-deficient mice on a high-fat diet
Xanthohumol (XN) improves cognition of wild-type rodents on a high-fat diet (HFD). Bile acids and ceramide levels in the liver and hippocampus might be linked to these effects. XN modulates activity of the nuclear farnesoid X receptor (FXR; also known as NR1H4), the primary receptor for bile acids....
Autores principales: | Kundu, Payel, Paraiso, Ines L., Choi, Jaewoo, Miranda, Cristobal L., Kioussi, Chrissa, Maier, Claudia S., Bobe, Gerd, Stevens, Jan F., Raber, Jacob |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Company of Biologists Ltd
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9713832/ https://www.ncbi.nlm.nih.gov/pubmed/36353888 http://dx.doi.org/10.1242/dmm.049820 |
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