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In vitro systems to study inborn errors of immunity using human induced pluripotent stem cells

In the last two decades, the exponential progress in the field of genetics could reveal the genetic impact on the onset and progression of several diseases affecting the immune system. This knowledge has led to the discovery of more than 400 monogenic germline mutations, also known as “inborn errors...

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Detalles Bibliográficos
Autores principales: Nikolouli, Eirini, Reichstein, Janne, Hansen, Gesine, Lachmann, Nico
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9713844/
https://www.ncbi.nlm.nih.gov/pubmed/36466870
http://dx.doi.org/10.3389/fimmu.2022.1024935